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Muscular Dystrophy

A. WHAT IS MUSCULAR DYSTROPHY?

Muscular Dystrophy encompasses a group of genetic disorders which are characterised by progressive loss of muscle mass and subsequent weakness. Dystrophy is coined from the Greek word which essentially means ‘bad nourishment’.
Early detection of muscular dystrophy started with a study by Sir Charles Bell, on the increasing weakness of the muscles of young boys, in 1830. This study on Muscular Dystrophy talks about a set of less than 30 genetic diseases that can lead to an alarming rate of increasing weakness of skeletal muscles applied through all voluntary movements. All these different ailments differ through the arrival stage, seriousness and prototype of muscles that are affected. All the manifestations of muscular dystrophy worsens as the muscles continually deteriorates and starts to weaken, and hence, it is considered as a “progressive muscular disorder”.
TYPES OF MUSCULAR DYSTROPHIES
  • Duchenne Muscular Dystrophy (DMD)
  • Becker Muscular Dystrophy (BMD)
  • Congenital Muscular Dystrophy (CMD)
  • Distal Muscular Dystrophy (DD)
  • Emery-Dreifuss Muscular Dystrophy (EDMD)
  • Limb-Girdle Muscular Dystrophy (LGMD)
  • Facioscapulohumeral Muscular Dystrophy (FSHD)
  • Moytonic Dystrophy (DM)
  • Oculopharyngeal Muscular Dystrophy (OPMD)

CAUSES OF MUSCULAR DYSTROPHY

Muscle weakness is generally caused when the cells that are used to sustain the muscles are no longer capable for their functionality. This, furthermore, leads to increasing weak points of the muscles and its disorder. The causes of Muscular dystrophy are as follows:

Muscular Dystrophy can be classified in these 3 ways -
This inheritance takes place when both parents pass a defective gene and a normal gene respectively to their child.
This inheritance means that both parents can transmit and transfer on the defective gene. It means that both the parents must hold one defective gene but remain unaffected by the disorder.
When a mother carries the affected gene on one of her two X chromosomes and passes it to her son.

B. STEM CELL THERAPY FOR MUSCULAR DYSTROPHY

Stem Cell Therapy has a promising potential to transmit progressive muscle proteins and restore the stem pool, thus, being the right muscular dystrophy treatment in India approach due to MD’s for deteriorative nature.

Stem cells have the capacity to convert into any type of body cell and undergo self regeneration.

The capacity of adult muscle to undertake renewal is largely credited to a distinctive subpopulation of muscle cells, called satellite cells. These cells are believed to be the chief cell type associated with skeletal muscle regeneration.

Stem cell treatment for muscular dystrophy contributes to tissue remodelling, inflammation reduction and prevention of cell death.

Muscular dystrophy treatment in India follows this mechanism:

  • Differentiation and cell fusions
  • Secretion of cytokines
  • Increase oxygen supply and contribute to vascularisation in the damaged area

THE NEUROGEN OUTCOME

Muscular dystrophy can wear out the emotional, physical and financial condition of the patients, as well as their caregivers. Cell therapy for muscular dystrophy in India at NeuroGen Hospital has come up as a successful treatment option after years of research and study. This is an incredible leap for not just muscular dystrophy treatment in India, but also the world!

THE OVERALL IMPROVEMENTS THAT ARE SEEN IN PATIENTS AFTER CELL THERAPY ARE

  • Increased trunk muscle strength
  • Limb strength on manual muscle testing and balance
  • Improvements in ambulation
  • Improved hand function
  • Increase in stamina
  • Better trunk balance

TREATMENTS THAT FOLLOW

The session of stem cell treatment for Traumatic Brain Injury in India together with neurorehabilitation facilitates in restoring the neural network by restoring the cells that are lost and all other cells present in the tissues of the brain. The patients who have experienced an acute Head Injury / Traumatic Brain Injury can restore their old life back through these two successful programs.
  • Physiotherapy
  • Occupational Therapy
  • Dietary Modifications
  • Art Based Therapies
  • Aquatic Therapy
  • Sensory Therapy
  • Speech Therapy
  • Special Education
  • Group Therapies / Motivational Workshops
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